Arduino enthusiast Jake has created an interesting ambient backlighting system for his dual-monitor setup. Using software that divides the monitors up into 32 seperate areas, the data is fed to a pythong application which converts the screen display data to commands that are sent to an Arduino. This in turn then controls RGB LED strips mounted behind the monitors for the lighting effects. Although it's more of a decoratrive project, the interaction between python and Arduino is an interesting code example. View Jake's video below for a quick explanation and demonstration:
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